Wednesday, November 22, 2006

Mesothelioma Asbestos Information


Mesothelioma is a serious and rare form of lung cancer. It is most frequently seen in men between the ages of 50 to 70. Women are affected far less frequently. In the US, between 2000 and 3000 cases are diagnosed each year. Estimates suggest that the incidence of mesothelioma for every 100,000 in the US is about 1.8 and 0.9 internationally. This form of cancer affects people of every race equally. The number of people who have been diagnosed with mesothelioma has increased significantly in the past 30 years. Although many advances in treatment have been made, there is no cure for this type of cancer.


In mesothelioma, the cells of the mesothelium become cancerous and grow out of control. The mesothelium is a protective, two-layered membrane that covers the internal organs of the body including the lungs, heart and abdominal organs. Between these layers, the cells produce fluid, which allows easy movement of the heart and lungs within the chest cavity. The layer that covers the lungs is called the pleura, and the layer that covers the heart is called the pericardium. The peritoneum lines the abdominal cavity. Mesothelium also lines the male and female reproductive organs. Mesothelioma can affect any of these cells, but is usually seen in the pleural or peritoneal mesothelium. The most common form of mesothelioma is pleural.


The primary risk factor for developing mesothelioma is exposure to asbestos. Between 70-80% of people diagnosed with mesothelioma have been exposed to asbestos, usually in the workplace. Although it is possible to develop mesothelioma without any exposure to asbestos, it is very rare. While one person for every million people in the US will be diagnosed with mesothelioma, about 7-13 men who have been exposed to asbestos will be diagnosed with the disease. Symptoms frequently take 20 years to develop, but can take as long as 50 years to occur.



When cancerous cells invade the mesothelium, it becomes increasingly difficult to breathe. In the pleural form of mesothelioma, tumors growing in the mesothelium cause pleural effusions, which prevent the smooth movement of the lungs and other organs in the chest. Peritoneal mesothelioma invades the abdominal cavity and can cause loss of appetite weight loss, nausea and vomiting. Most patients seek medical care after having symptoms only 4-6 months.

Mesothelioma is a very aggressive form of cancer. Because it takes so long for symptoms to appear it can spread to the other organs in the chest, the chest wall and into the lymph nodes. The cancerous cells spread, or metastasize from the mesothelium into other parts of the body and damage internal tissues and organs. Treatment is more effective when the disease is detected early



Treatment is aimed at reducing the size of tumors, and relieving symptoms. Chemotherapy, radiation treatment and surgery are some of the traditional treatment strategies used to help patients live longer, with fewer symptoms. New advances in photodynamic therapy and immunotherapy give hope for prolonging the lives of patients with mesothelioma. On average, however, the life expectancy after being diagnosed with mesothelioma is less than one year.

Symptoms of Mesothelioma

The long latency period attached to mesothelioma means that the symptoms of this disease can take many years to manifest, making both diagnosis and effective treatment very difficult. And even when the symptoms do become evident, which can take several decades, the symptoms are so generalised and non-specific that they could be put down to any number of more common diseases. This makes it hard for even experienced doctors to make a quick and conclusive diagnosis with mesothelioma patients. The symptoms of this disease can often be confused with pneumonia during its early stages.

Some of the most common symptoms of pleural mesothelioma (which is the most common form of the disease) are shortness of breath and chest pains. This may be accompanied by a persistent cough, and all of these symptoms stem from the build up of fluid between the lining of the lung and the chest cavity. This is known as pleural effusion. This type of the disease starts in the chest cavity and can then spread to other parts of the body. Pleural mesothelioma sufferers may also begin to display severe breathing difficulty, weight loss and fever as well as trouble swallowing and even swelling of the face and neck. Some patients may also develop a rasping voice and start coughing up blood. However, there are other patients that may not show any significant symptoms at all.

The symptoms for patients who suffer from peritoneal mesothelioma (a rarer form of the disease) are slightly different. This type of the disease starts in the abdomen and can spread form there. Patients of peritoneal mesothelioma can display abdominal pain and swelling, nausea, loss of appetite and vomiting. They can also suffer breathing problems, and chest pain in addition to these symptoms. These symptoms result from tumours that lean against the abdominal wall. Bowel obstruction, anaemia, fever and problems with blood clotting may also affect peritoneal mesothelioma patients.

The rarest form of this disease is pericardial mesothelioma, which starts in the cavity surrounding the heart. With pericardial mesothelioma, the tumours grow in the tissues that surround the heart and can spread from there. Pericardial mesothelioma sufferers may experience chest pain, shortness of breath, persistent coughing and palpitations.
As the disease moves into the later stages, the symptoms for all types of mesothelioma become more acute and obvious, although they can still often be put down to another illness. It is therefore important for patients to inform their doctor if they have been exposed to asbestos at any point – or even if they suspect they may have been exposed to asbestos. This will enable the doctor to make a more informed diagnosis rather than basing his diagnosis on guess work. It is also important not to ignore any of these symptoms, especially if they are experienced over a long period. Many people can be exposed to asbestos inadvertently (e.g. through the clothes of someone that has worked with asbestos) so it is important to visit your doctor should any of these symptoms manifest.

With pleural mesothelioma being the most common form of the disease, the symptom associated with this form of the cancer are the most common ones that are displayed by patients. However, it is important to be fully aware of the symptoms for all three types of mesothelioma, particularly for those who have worked in high risk professions where they may have been exposed to asbestos. Most people who have worked with asbestos in the past do not begin to show symptoms of mesothelioma until thirty to forty years later. By this time, the disease is already spreading and with the delay in diagnosis, makes it impossible to treat in many cases before it is too late. However, the cause, effects and symptoms of mesothelioma are now becoming more widely known by professionals and lay people. This awareness, coupled with the current clinical trials that are being carried out by a variety of organizations gives patients the hope that an effective treatment will one day be available for all stages of the disease.

Mesothelioma Treatments

With new clinical trials being introduced on a regular basis, there are a variety of treatments being used on mesothelioma. The treatment used is dependant upon a variety of factors, including the extent of the disease, the age and medical history of the patient, and the location and type of the mesothelioma.

The most common treatments are:
- Surgery, where the tissue in the affected area is cut out. This may involve removing part of the organ depending on the size of the affected area.
- Radiation treatment, which involves the use of radiation treatment to kill off the cancerous cells in the affected area.
- Chemotherapy, which is the use of drugs in the body used to kill off the cancerous cells.

Pneumonectomy

A surgical procedure, known as pneumonectomy, can be used for pleural mesothelioma and involves the removal of the diseased lung. An extra-pleural pneumonectomy may be necessary depending upon the spread of the disease, and this may involve the removal of parts of the diaphragm as well as the lung. There is a high risk factor with this surgery, and its viability is dependant upon the patient’s overall health, smoking habits and the extent of the asbestos exposure. A pleurectomy is another type of surgery that may be used, and here part of the chest, abdominal lining and surrounding tissue may be removed.

Radiation treatment

Radiation treatment , which gives the benefit of treating the affected area without exposing the healthy cells and tissue, is another treatment used to treat mesothelioma. This is a speedy and commonly used method for many types of cancer, as well as mesothelioma. It works through the placements of radioactive sources in the affected area, which then give out radiation to kill off the abnormal cells. The radiation continues to transmit for around a year, working to destroy the tumour. Radiation therapy can be used alongside surgery, or if the patient is not well enough for surgery can be used alone.

Chemotherapy treatments

Chemotherapy treatments can be administered in the form of pills or injected medication. The downside of chemotherapy is that the drugs used can contain high toxicity levels and can therefore make patients quite ill. Side effects can include nausea, vomiting, hair loss, weight loss and physical fatigue. There are also a number of post-chemo drugs that are used to alleviate the side effects of the chemotherapy. Because chemotherapy drugs are not targeted towards a specific area, they are left to make their way through the body and find the affected area. This means that they are also able to affect tissue and cells that are unaffected by the disease, which can again cause side effects.

Palliative Therapies

Palliative Therapies may also be used on mesothelioma patients. These therapies entail draining excess fluid from the patient through the use of a needle and suction. To prevent further fluid accumulation drugs may be fed through a tube into the chest following the fluid drainage.

Often, a combination of treatments and a cocktail of drugs have to be used in order to treat mesothelioma patients. Again, the types of treatment used will be dependant upon the age and physical health of the patient as well as upon how far the disease has spread and where it is located.

The above are some of the most common treatments used for the treatment of mesothelioma, but they do not always work effectively on mesothelioma patients. Because of this, sufferers of mesothelioma may be offered treatment as part of a clinical trial as opposed to any of the traditional treatments. With new mesothelioma cancer treatments are continually being tested through medical research studies, it is hoped that an effective treatment will soon be discovered. These clinical trials enable professionals to asses whether the treatment being tested may one day be effective for general use to treat mesothelioma. And these clinical trials also give hope to the patients who allow themselves to be used as guinea pigs, enabling them to be a part of this important research and find a drug that may help them and others in the same situation.

Mesothelioma and the LAW
Over recent years, we have seen many multi-million dollar compensation payouts to victims of mesothelioma, the asbestos exposure related cancer. This is a relatively new disease, both in terms of medical and legal awareness, and sufferers of mesothelioma are finding that they are entitled to a hefty compensation in many cases. And to help these victims get their dues, many lawyers and law firms have been trained and set up to deal with mesothelioma claims in order to get mesothelioma sufferers the compensation to which they are entitled.

Why are mesothelioma victims entitled to compensation? Well, most cancers not the fault of an outsider. Heavy smokers may get cancer through smoking, which is their own choice. Other types of cancer, such as breast, cervical and prostate are not anybody’s fault, although vigilance and regular check ups can help to identify these caners early on and therefore treat them effectively. However, mesothelioma is a totally different type of cancer. This is a cancer that could have been prevented, and it is the fault of outsiders – namely the irresponsible firms that made no efforts to protect their workers against the hazards of working with asbestos. You see, mesothelioma is the result of regular exposure the asbestos dust and fibres, which are ingested into the system and corrupt the cells of the protective lining that surround major organs – the mesothelium. The cancer lies dormant for many decades, and victims do not realise until thirty or forty years later that they have the disease. By the time tests have been done and a diagnosis has been made, it is often too late to do anything constructive about it, and the patient is left with just a short time to live – typically 4-24 months.

These mesothelioma lawyers are here to help victims of mesothelioma to get cold, hard cash from the companies responsible for their doomed fate. This compensation will help to cover medical expenses and pain and suffering. But, perhaps most importantly, it helps to provide financial stability and security for the victim’s loved ones after he or she has passed away.

The payouts for mesothelioma have run from hundreds of thousands of dollars, to multi-million dollars. But the mesothelioma sufferer must ensure that the chances of success are optimised by seeking legal advice and assistance as soon as the diagnosis has been confirmed. Most states only provide a certain time within which you can file a mesothelioma lawsuit, so it is vital that you do this immediately. Your lawyer will also need the extra time to put your case together and carry out any necessary research. Time is of the essence where mesothelioma lawsuits are concerned, and just a few days could make the difference between financial security for your family and no compensation at all.

If you are concerned about not having any money up-front to pay for legal costs, don’t be. The vast majority of mesothelioma lawyers work on a contingency fee basis. This means that they do not take any money from you up-front. And if your case is unsuccessful they will not take any money from you at all. You only have to pay the lawyer if and when you receive compensation. Your lawyer will then be entitled to a percentage of the compensation. And, although the cut to which the lawyer is entitled can seem high – generally around the 35% mark – it does mean that you don’t have to worry about paying in order to file for compensation and you have nothing to lose if you don’t get any compensation.

Your mesothelioma lawyer will also be able to give you support and advice with regards to your illness. The experienced mesothelioma lawyers have already built up a network of contacts within the field; not only for legal support but for all types of support and advice. This network means that your lawyer can process your claim more quickly than a lawyer who has little or no knowledge or experience in dealing with mesothelioma lawsuits. The experienced lawyer will also be able to point you in the right direction for additional support services and support groups

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